The castaway William Fitzgerald is rescued in an island by Dr. Charles Girard, his lonely wife Frances Girard and his assistant Walter Perrera. A couple of days later, Fitzgerald has an affair with Frances and realizes that the unethical and insane Dr. Girard is developing sick experiments and transforming a panther into a man-like creature. Meanwhile, the monster escapes from the laboratory, killing Walter and the servant Celina and seizing and capturing Frances with him. Fitzgerald and Dr. Girard chase the being along the night.
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