Young nurse, Charlotte Beale, arrives at the "Stevens Sanitarium and home for the mentally ill" after accepting a job offer from the Sanitarium's head doctor, Dr. Roy Stevens, who is known for his unorthidoxed methods of treating the mentally insane. Upon arrival, she is greated with a stunning revelation; Dr. Stevens and the majority of the staff has been murdered by one of the patients, and the Sanitarium itself is on the brink of takeover. The only remaining staff member, Dr. Geraldine Masters, has resumed control of the Sanitarium, but can hardley remain control of the patients, who are all forgotten members of society deemed "hopelessly" damaged psychologically. Willing to assist Dr. Masters with the task of keeping the patients under control, she begins to get to know each of the patients, and grows particularly fond of a child-like man named, Sam.
As she continues to befriend, Sam, strange things begin to occur and Charlotte soon realizes things may not be as the appear, and the sense of grave danger becomes imminate.