Warner Bros. has set Alex Holmes to rewrite and direct The Interpretation of Murder, an adaptation of the Jed Rubenfeld novel. The story follows a Sigmund Freud protege who discovers a trail of sadistic murders in turn-of-the-century New York. Chris Kyle wrote the first draft of the screenplay. The novel was published in 2007 by Picador. Paula Weinstein is producing. The deal marks the first studio project for Holmes, who co-wroe, helmed and was exec producer of “House of Saddam,” a dissection of the ruthless reign of Iraqi leader Saddam Hussein. The mini aired on HBO in the U.S.