Noah Greene (Josh Danziger) awakens from a two-year coma. His memories are hazy; even as he rehabilitates himself, he remains lost in his own life. As Noah digs deeper into his half-remembered life, he is forced to confront the suspicions of those around him, as well as a pair of shattering tragedies that both bind him to and drive him away from the girl he loves. The first of these – a school bus accident when they were young children – has forever connected him to his playmate Emily Gates (Olesya Rulin). The result of the accident is a rare but real disorder called folie à deux (referred to as ICD-10, F.24), where the traumatized Emily suffers disturbing and precognitive visions for the rest of her life – visions which Noah also experiences, but only in proximity to Emily.
As Noah returns to his hometown, determined to discover the cause of his injury and memory loss, he re-connects with Emily. Together, Noah pieces together the nature of the relationship they enjoyed as teenagers: warm, familiar, achingly tender… a closeness that should have blossomed into romance, save for the catastrophes of the past.