Maniac (2018, Netflix Series)
Two strangers are drawn to a mysterious pharmaceutical trial that will, they're assured, with no complications or side-effects whatsoever, solve all of their problems, permanently. Things do not go as planned.
Fukunaga's long-form cinema follow up to True Detective with Emma Stone/Jonah Hill/Justin Theroux/Sally Field. Theroux plays a more comedic mad scientist type, his best performance and probably the best this year, hilarious. It's a weird mishmash of sci-fi/dramedy that's unlike most things but something that would have been done decades ago, if that makes sense. Last episode was very powerful, overall one of the more effective portraits of mental health and anxiety out there.