We had recently learned that Morgan Creek Entertainment was working on a small screen adaptation of David Cronenberg‘s Dead Ringers, and today brings word via Deadline that Rachel Weisz has signed on to both star in and exec produce the TV series adaptation.

Billed as “a reimagining with a gender swap,” the project has been given a straight-to-series order by Amazon. It comes from Weisz, Alice Birch, Annapurna Television and Morgan Creek.

Deadline describes, “In Dead Ringers, written by Birch, The Mantle twins, played by Weisz, are the most successful, brilliant and extraordinary people you’ve never met. Identical from head to toe, these two OB-gyn’s are on a mission to change the way women birth, starting with Manhattan. Drugs, pioneering but very much illegal medical research, sex and falling in love, this drama based on the David Cronenberg 80s cult classic, takes us to darker and stranger territory than we could have possibly imagined.”

The site also notes that the series “is said to explore themes like women’s health and the issues it faces, including underfunding, as it focuses on the two professional women, the Mantle twins, who are excellent at their jobs while also trying to navigate life outside of work. In the series, the Mantle twins share everything: drugs, lovers, and an unapologetic desire to do whatever it takes, including pushing the boundaries on medical ethics in an effort to challenge antiquated practices and bring women’s healthcare to the forefront.”

Jeremy Irons starred in the 1988 film as the twin gynecologists.

Rachel Weisz in ‘The Favourite’